Nope... the only major difference I have seen is some radiators have the inlet moved a little more to the inside then others. Mostly on 200's.
Nope. I've got a 200 I6 rad in mine hooked to the 302. Had to have a special hose and bushing for the bottom, water pump is 1 3/4 and rad is 1 1/4, top I used the T Bird hose and just cut it to fit, same size on both water neck and rad.
my stock radiator was a 2 row.. it had the lower fitting on the driver;s side.. the aftermarket 1967 mustang 4 row radiator i bought from radiators.com had the lower outlet on the passenger side and i had to have the lower outlet moved to the drivers side..